右侧乳腺外上象限有回声可见无回声,大小约0.68cm*0.31cm,边界清,内回声不均,后方轻度增强。

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A new oxygen reduction electrocatalyst of barium lanthanide cobaltate for composite cathodes of proton-conducting ceramic fuel cells
Corresponding authors
Department of Energy and Hydrocarbon Chemistry, Graduate School of Engineering, Kyoto University, Nishikyo-ku, Kyoto 615-8510, Japan
This is the first report of the application of the barium lanthanide cobaltate of Ba4Sr2Sm2Co4O15 (BSSC) as an oxygen reduction electrocatalyst of proton-conducting ceramic fuel cells. In this study, composite cathodes of Ba4Sr2Sm2Co4O15–BaCe0.5Pr0.3Y0.2O3-δ (BSSC–BCPY) were developed by varying the mixing ratio. The BSSC–BCPY composite with the optimal composition exhibited a polarization resistance of 0.19 Ω cm2, 0.31 Ω cm2, and 0.59 Ω cm2 at 600 °C, 550 °C, and 500 °C, respectively, for the symmetrical cell test in 3% humidified synthetic air. Its activation energy was evaluated to be 68.5 kJ mol-1. In this composite system, BSSC appeared to serve as an active phase for the dissociative adsorption of oxygen. The operation of the anode-supported cell employing the optimized cathode was successfully demonstrated at 600 °C, and a maximum power density of 197 mW cm-2 was achieved upon feeding synthetic air and humidified hydrogen to the cathode and anode, respectively. Finally, the chemical stability of the BSSC–BCPY composite in a CO2-containing atmosphere was evaluated.
The article was
received on 03 May 2018,
accepted on 28 Jun 2018
first published on 29 Jun 2018
Article type:
J. Mater. Chem. A, 2018,6,
ReferenceManager
T. Matsui, K. Manriki, K. Miyazaki, H. Muroyama and K. Eguchi,
J. Mater. Chem. A, 2018,&6, 14188
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This may take some time to load.甲状腺结节
来自于:辽宁|
提问时间: 15:51:51|
病情描述:
2012年六月份发现的
,当时检查单子如下:
号 曹县人民医院
甲状腺双侧叶大小形态正常,左侧可见大小约0.32 x 0.19 cm低回声团状,边界清,内回声不均匀,右侧可见大小约0.86 x 0.69 cm低回声团状,边界清,内回声不均匀。
CDFI:周围可见血流信号环绕。
双侧颈部可见多个低回声结节,右侧较大者约2 x 0.68 cm,左侧较大者约 0.91 x 0.43 cm。
诊断意见:甲状腺良性结节;甲状腺;双颈部淋巴结增大。
菏泽市立医院
B超检查单:
甲状腺左侧叶厚1.1cm,宽1.1cm;右侧叶厚1.2cm,宽1.5cm;狭部0.2cm。
甲状腺双侧叶大小正常,形态规则,包膜光滑。实质回声粗略、欠均匀。
甲状腺右侧叶上极可探及0.2x0.1cm无回声区,边界清,内见一点状强回声,透声尚可。甲状腺右侧叶中上部另见一无回声区,范围约0.8x0.6cm,透声较差,内充满弱回声,内另见两处强回声斑,后方略伴彗星尾征,内未见明显血流信号显示。甲状腺左侧叶内可见多个无回声区,大者约0.3x0.2 cm,内见一点状强回声。
甲状腺双侧叶血流信号未见明显异常。
颈部多切面检查:右侧颌下区可探及两处低回声结节,大者约2.1x0.6 cm,淋巴门结构清晰。左侧颈部未见明显囊实性包快。
诊断结果:甲状腺双侧叶囊性结节(考虑结节性甲状腺肿,建议定期复查),右侧颌下增大淋巴结。
号 曹县人民医院 B超单:
甲状腺双侧叶及狭部大小形态正常,实质内回声均匀,右侧叶内可见一大小约0.45x0.31 cm低回声结节,内可见大小约0.1 x 0.1 cm强回声光斑。
右侧颈部见多个低回声结节,较大者约1.5 x0.69 cm,边界清。左侧颈部见多个低回声结节,较大者约1.2 x 0.4 cm,边界清。
诊断意见:
甲状腺右侧叶结节并;建议定期复查;双侧颈部轻度肿大淋巴结。
号 商丘市第一人民医院 B超单:
甲状腺左侧叶大小41x 13x11 mm,甲状腺右侧叶大小42x15x15 mm,狭部厚3mm,甲状腺双侧叶大小正常,形态规则,右侧叶内见一低回声结节,大小约6 x 4 mm ,边界清晰,未见血流信号。左侧叶内见一无回声囊,大小约2 x2 mm,内见强回声光点,余甲状腺回声均匀,双侧叶内血流信号正常。
检查结果: 甲状腺右侧叶结节,疑是腺瘤。甲状腺左侧叶小囊肿。
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妇产科医生抑郁模型大鼠nesfatin-1水平及其在抑郁发病中的作用机制--《武汉大学》2017年硕士论文
抑郁模型大鼠nesfatin-1水平及其在抑郁发病中的作用机制
【摘要】:目的:研究抑郁模型大鼠及正常大鼠外周血浆及中枢下丘脑、脑干nesfatin-1水平的病理生理差别;探索抑郁模型大鼠nesfatin-1 水平变化与其情绪行为变化的关联;探查nesfatin-1水平变化与大鼠抑郁样行为及其与下丘脑-垂体-肾上腺皮质轴(hypothalamic pituitary adrenalaxis,HPA)及单胺递质合成酶的相关性;探索nesfatin-1在抑郁发病中的可能作用机制。方法:采用随机数字表法将12只成年雄性SD大鼠随机分为正常对照组(NC组)和抑郁模型组(CUMS组),采用旷场实验(open field test,OFT)评估两组大鼠造模前的行为,初步统计两组大鼠行为学无明显差异时则造模开始,CUMS组予以连续5周7种不同的慢性轻度不可预见性刺激(chronic unpredictable mild stress,CUMS),NC组则正常喂养,5周后采用糖水偏好实验(sucrose preference test,SPT)、强迫游泳实验(forced swimming test,FST)分别同时评估两组大鼠的行为,收集大鼠的血浆,取其新鲜的下丘脑组织及脑干组织,检测两组大鼠血浆皮质酮及下丘脑促肾上腺皮质激素释放激素(corticotropin releasing hormone,CRH)水平以评估HPA的活性,比较两组大鼠脑干酪氨酸羟化酶(tyrosine hydroxylase,TH)及色氨酸羟化酶(tryptophan hydroxylase,TPH)表达水平变化,检测血浆、下丘脑、脑干nesfatin-1水平,比较两组大鼠nesfatin-1水平变化,血浆指标检测方法采用酶联免疫吸附实验(Enzyme linked immune-absorbent Assay,Elisa 法),中枢脑组织指标检测采用蛋白质免疫印迹(western blot)法,将nesfatin-1水平与大鼠的行为学指标、HPA轴及单胺递质合成酶指标分别进行相关性分析。结果:(1)大鼠行为学分析结果:造模前大鼠行为学分析结果:CUMS组体重[(307.00±11.23)g]相比于NC组[(306.00±13.52)g],两组大鼠体重差异无统计学意义(t=-0.139,P=0.892),OFT中直立次数CUMS组[(7.83±5.71)次]对NC组[(9.83±3.82)次],差异无统计学意义(t=0.714,P=0.492),OFT 中水平运动总距离,CUMS 组[(.53)cm]对 NC 组[(.15)cm],差异无统计学意义(t=-0.698,P=0.501)。造模后大鼠行为学分析结果:与NC组相比,CUMS组大鼠体重增长明显减慢[(85.17±28.31)g]对[(121.00±12.60)g],差异具有统计学意义(t=2.830,P=0.018),SPT中,CUMS组大鼠糖水偏嗜度明显降低[(0.68士0.06)%]对[(0.91±0.05)%],差异具有统计学意义(t=2.830,P=0.000),FST中,CUMS组大鼠强迫游泳不动时间明显延长[(108.83±18.90)s]对[(65.83±11.16)s],差异具有统计学意义(t=-4.798,P=0.001)。(2)nesfatin-1水平检测结果:相比于NC组,CUMS组大鼠血浆nesfatin-1水平明显增高[(3.50±1.23)ng/ml]对[(1.80±0.87)ng/ml],差异具有统计学意义(t=-2.778,p=0.020),同时下丘脑及脑干中nesfatin-1蛋白相对表达水平也显著升高,分别为(0.17±0.06)对(0.10±0.03)及(0.22±0.12)对(0.15±0.40),差异具有统计学意义(=-2.450,P=0.037 及 t=-4.158,P=0.002)。(3)HPA轴相关指标检测结果:两组相比较,外周血中CUMS组大鼠血浆皮质酮水平(166.53±5.34pg/ml)显著高于NC组(132.71±14.31pg/ml),差异具有统计学意义(t=-5.424,P=0.000),中枢下丘脑CRH蛋白相对表达水平CUMS组与NC组无明显差别(P=0.537)。(4)脑干TPH及TH蛋白相对表达水平:脑干TPH蛋白及TH蛋白相对表达水平相比NC组,CUMS组表达均显著下降,TPH蛋白表达为(0.29±0.13)对(0.52±0.05),差异具有统计学意义(t=4.047,P=0.002),TH蛋白表达为(2.69±0.27)对(3.27±0.16),差异具有统计学意义(t=4.584,P=0.001)。(5)相关分析结果:将nesfatin-1水平与大鼠行为学指标进行相关分析发现,CUMS组大鼠血浆nesfatin-1水平与强迫游泳不动时间呈正相关(r=0.922,P=0.009),与大鼠体重增长量呈负相关(r=-0.825,P=0.043),与糖水偏嗜度无相关关系(P0.05)。同时发现CUMS组大鼠血浆nesfatin-1水平与血浆皮质酮水平呈正相关(r=0.827,P=0.042),脑干中CUMS组大鼠nesfatin-1蛋白表达水平与TPH蛋白表达水平呈负相关(r=-0.832,P=0.044),但与TH蛋白表达水平无相关关系(P0.05)。结论:抑郁模型大鼠外周血及中枢下丘脑、脑干nesfatin-1水平皆明显增高,这种病理性改变可能参与抑郁样行为的发生过程,nesfatin-1的改变可能通过影响HPA轴介导抑郁样行为。脑干nesfatin-1蛋白表达水平增高可能通过影响TPH蛋白表达水平,进而影响5-HT的合成,这可能是影响抑郁样行为的另一条重要的神经内分泌通路。
【学位授予单位】:武汉大学【学位级别】:硕士【学位授予年份】:2017【分类号】:R749.4;R-332
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Optical variability in IBL S5
during the
Kaur, Navpreet; Baliyan, Kiran S.; Chandra, S.; Sameer; Ganesh, S.
With an aim to explore optical variability at diverse timescales in BL Lac source S5 , it was observed for 46 nights during 2013 January 14 to 2015 June 01 when it underwent two major outbursts. The observations were made using the 1.2 m Mount Abu InfraRed Observatory telescope mounted with a CCD camera. On 29 nights, the source was monitored for more than 2 hr, resulting in 6256 data points in the R band, to check for the intra-night variability (INV). Observations in the B, V, and I bands with 159, 214, and 177 data points, respectively, along with daily averaged R-band data are used to address inter-night and long-term variability and the color behavior of S5 0716+71. The study suggests that the source shows significant INV with a duty cycle of more than 31% and night-to-night variations. The average brightness magnitudes in the B, V, R, and I bands were found to be 14.42(0.02), 14.02(0.01), 13.22(0.01), and 13.02(0.03), respectively, while S5
was historically brightest with R = 11.68 mag on 2015 January 18, indicating that the source was in a relatively high state during this period. A mild bluer-when-brighter behavior, typical of BL Lacs, supports the shock-in-jet model. We noticed larger amplitudes of variation when the source was relatively brighter. Based on the shortest timescale of variability and causality argument, the upper bound on the size of the emission region is estimated to be 9.32 ? 1014 cm, and the mass of the black hole is estimated to be 5.6 ? 108 M ?.
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