Nationwide Epidemiology and Prognosis of Dialysis-requiring Acute Kidney Injury (NEP-AKI-D) study: Design and methods - Shiao - 2015 - Nephrology -
Wiley Online Library
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AimAcute kidney injury (AKI) carries increasing incidence rate worldwide and increases the risk of developing end-stage renal disease (ESRD) as well as the medical expenses during the post-AKI course. The Taiwan Consortium for Acute Kidney Injury and Renal Diseases (CAKs) has thus launched a nationwide epidemiology and prognosis of dialysis-requiring acute kidney injury (NEP-AKI-D) study which prospectively enrolls critically ill patients with AKI. Through thoroughly evaluating the risk and prognostic factors of AKI, we hope to lower the incidence of AKI and ESRD from the perspective of AKI-ESRD interaction.MethodsThe CAKs includes 30 hospitals which distribute widely through the four geographical regions (north, middle, south, and east) of Taiwan, and have a 1:1 ratio of medical centers to regional hospitals in each region. The NEP-AKI-D study enrolls intensive care unit-based AKI patients who receive dialysis in the four seasonal sampled months (October 2014, along with January, April, and July 2015) in the included hospitals. The collected data include demographic information, pertaining laboratory results, dialysis settings and patient outcomes. The data are uploaded in a center website and will be audited by on-site principal investigators, computer logic gates, and the CAKs staffs. The outcomes of interest are in-hospital mortality, dialysis-dependency and readmission rate within 90 days after discharge.ConclusionsThe NEP-AKI-D study enrolls a large number of representative AKI patients throughout Taiwan. The results of current study are expected to provide more insight into the risk and prognostic factors of AKI and further attenuated further chronic kidney disease transiton.Total arterial revascularization with a single y-composite graft for triple-vessel disease:... - Abstract - Europe PMC
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Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
[):E382-6]
Journal Article, Comparative Study
10.1532/HSF98.
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Diseases (7)
Gene Ontology (1)[The use of simplified regional citrate anticoagulation in continuous veno-venous hemofiltration].
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FormatSummarySummary (text)AbstractAbstract (text)MEDLINEXMLPMID ListChoose DestinationFileClipboardCollectionsE-mailOrderMy BibliographyCitation managerFormatSummary (text)Abstract (text)MEDLINEXMLPMID ListCSVCreate File1 selected item: FormatSummarySummary (text)AbstractAbstract (text)MEDLINEXMLPMID ListMeSH and Other DataE-mailSubjectAdditional textE-mailAdd to ClipboardAdd to CollectionsOrder articlesAdd to My BibliographyGenerate a file for use with external citation management software.Create File
):313-6.[The use of simplified regional citrate anticoagulation in continuous veno-venous hemofiltration]. [Article in Chinese]1, , .1Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou 363000, Fujian, China.AbstractOBJECTIVE: To study the safety and effect of simplified regional citrate anticoagulation (RCA) in continuous veno-venous hemofiltration (CVVH).METHODS: Fourteen patients were treated with CVVH using simplified RAC. Simplified anticoagulation protocol included the addition of 4% sodium citrate into the replacement fluid. The citrate replacement fluid was infused in a speed of 2,000 ml/h or 3,000 ml/h, and at the same time 10% calcium gluconate and 25% magnesium sulfate were infused post filter or with venous pump into peripheral veins. Serum electrolytes, arterial blood gas analysis, coagulation at the beginning and 4, 8, 12 hours after the treatment were monitored. Patient's general condition was observed carefully. After treatment, blood volume in the hollow fiber filter was measured.RESULTS: Fourteen patients underwent altogether 34 times of this procedure for a total of 544 hours. Each treatment lasted 4-36 hours, with a mean of (16.0+/-7.5) hours. The filter was not changed for 30 procedures. After treatment, the blood volume in the filter was higher than 80% of the original volume. The life span of the filter was (14.79+/-5.98) hours on the average. Twelve hours after infusing citrate, there was a marked shortening of prothrombin time [PT, (12.2+/-1.2) s vs. (14.0+/-3.3) s], while plasma total calcium was increased markedly [(2.46+/-0.30) mmol/L vs. (2.07+/-0.36) mmol/L, both P&0.05]. There was no significant difference in activated partial thromboplastin time (APTT), thrombin time (TT), the concentration of Ca(2+) and Mg(2+), pH and base excess (BE). In one patient with hypoxemia the treatment was stopped due to the appearance of serious complications. No hypernatremia or metabolic alkalosis was found during the RCA in all the patients. No significant bleeding events attributed to RCA occurred.CONCLUSION: The simplified anticoagulation protocol by adding sodium citrate replacement fluid can be applied safely in replacement fluid&2,000 ml/h of CVVH without complications of hypernatremia and metabolic alkalosis caused by sodium citrate anticoagulation.PMID:
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External link. Please review our .Diagnosis, prevention and treatment of accidental and perioperative hypothermia.
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):307-22. doi: 10.1515/bmt-.Diagnosis, prevention and treatment of accidental and perioperative hypothermia., , .AbstractAccidental hypothermia and its variant, perioperative hypothermia, is a rather common clinical phenomenon in patients. This is surprising because the negative effects on clinical outcomes are well described and effective patient-warming devices are available today. The aim of this paper is to describe the physiologic background of accidental and perioperative hypothermia, the clinical relevance and existing prophylaxis and treatment options. Patient warming techniques will be discussed in detail. Remaining technical and clinical challenges and the need for further research will be addressed. We will present existing guidelines and standards and analyse the impact of accidental and perioperative hypothermia on cost effectiveness. PMID:
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