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polymorphous是什么意思
中文翻译英英解释adj.1.多形的。2.【化学】多晶型的。
例句与用法Posterior polymorphous corneal dystrophy多形性角膜后层营养不良Executive polymorphous suite行政复式套房Polymorphous light eruption多形性日光疹Deluxe polymorphous room豪华复式房Polymorphous storey , the balcony , mountain scene , fireplace are the greatest characteristic错层阳台山景壁炉是最大的特色。 Room intro about 313 guestrooms , included deluxe standard room , executive business suite , polymorphous suite and president suite酒店共拥有313间客房,包括豪华标准间行政商务套房复式套房和总统套房。 Polymorphous structure only intersects your living space again , change it from horizontal to vertical , and bring the fresh feeling远的空间感。复式结构不过是给你的居住空间以重新的划分，由横向转为纵向，角度的There are 100 guestrooms , such as 20 suites including one deluxe suite , 80 standard room and 19 polymorphous suites星河大酒店拥有100间舒适的客房，其中20套为套房， 80套为标准房，套房包括一间维多利亚豪华套房， 19套复式套房。 The most common form of this condition , polymorphous light dermatosis , generally affects areas of skin that have not got accustomed to the sun . its cause is high uva radiation这种情况下最常见的发病症状就是多形性光皮肤病，主要是病变区皮肤不适应太阳光，这是由强烈的紫外线照射引起的。 Hotels cover an area of 80 , 000 square meters , have 607 various types of guest rooms 587 standard rooms , 16 executive suites , 2 luxurious polymorphous double - deck suites , one president suite beside river among them酒店占地面积8万平方米，拥有各式客房607间其中标准房587间豪华套房16间豪华复式双层套房2间独立临江总统套房一栋。 更多例句：&&1&&&&
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All rights reservedMucosal Immunology - Abstract of article: Primary Heligmosomoides polygyrus bakeri infection induces myeloid-derived suppressor cells that suppress CD4+ Th2 responses and promote chronic infection
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AbstractPrimary infection with the gastrointestinal nematode Heligmosomoides polygyrus bakeri is chronic in C57BL/6 (B6) mice whereas challenge infection is rapidly eliminated. F4/80−CD11b+Gr+ cells, presumed to be neutrophils, were reported to accumulate around encysting larvae in intestinal tissue during primary infection, but their exact identity and role remain unclear. We observed significant increases in F4/80−CD11bhiGr1hi cells in mesenteric lymph nodes (MLNs) and spleen after primary but not a high proportion of these cells expressed Ly6G and Ly6C. These cells, which phenotypically resemble myeloid-derived suppressor cells (MDSC), increased in lamina propria (LP) early during primary infection. Increased MDSC were associated with low numbers of alternatively activated macrophages (AAMØ) in LP and CD4+GATA3+ T cells and AAMØ in MLN and spleen. Purified CD11c−CD11b+Gr1+ cells from H. polygyrus bakeri-infected mice suppressed OVA-specific CD4+ T-cell proliferation via a nitric oxide-dependent mechanism and parasite-specific IL-4 secretion in vitro. Adoptive transfer of CD11c−CD11b+Gr1+ cells from mice with primary infection resulted in significantly higher adult worm burdens and increased egg production in naïve B6 recipients infected with H. polygyrus bakeri. Altogether, these findings indicate that primary H. polygyrus bakeri infection induces a novel subset of MDSC that suppress CD4+ Th2 responses and promote chronic infection.
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ADVERTISEMENTSusceptibility of adult Heligmosomoides polygyrus to intestinal inflammatory responses induced by heterologous infection
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, February 1992, Pages 75-86
Susceptibility of adult Heligmosomoides polygyrus to intestinal inflammatory responses induced by heterologous infection
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*MRC Experimental Parasitology Research Group, Department of Life Science, University of Nottingham, University Park, Nottingham NG7 2RD, U.K.?W. Stefanski Institute of Parasitology of the Polish Academy of Sciences, Pasteura 3, P.O. Box 153, 00-973 Warszawa, Poland
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Adult H. polygyrus are capable of surviving for many months after primary exposure of mice to infective larvae, raising the possibility that worms of this species have inherent resistance to intestinal immune responses. Accordingly experiments were carried out to determine whether H. polygyrus are resistant to the inflammatory changes elicited during the acute phase of the intestinal response to Trichinella spiralis. Adult worms were expelled from mice when their presence coincided with the most intense phase of inflammation elicited by T. spiralis. The effect was dose-dependent with more intense T. spiralis challenge resulting in a correspondingly greater loss of H. polygyrus. Even the less pathogenic species T. pseudospiralis elicited a response of sufficient intensity in NIH mice to cause the expulsion of H. polygyrus from concurrently infected animals. Tissue larval stages of H. polygyrus were protected from expulsion by their location deep in the intestinal walls and the maximum detrimental effect against H. polygyrus was observed during the adult phase or during the establishment of larvae. Acceleration of the response to T. spiralis in immune challenged mice resulted in earlier loss of H. polygyrus. When the expulsion of T. spiralis was delayed (e.g. from slow responder C57BL/10 mice) the loss of H. polygyrus took place correspondingly later. These experiments demonstrate unequivocally that mouse strains which normally tolerate chronic infections with H. polygyrus have the capacity to mount intestinal inflammatory responses of sufficient vigour to remove the worms but that this potential is not normally realized. However, the observation that some H. polygyrus always survived even when the response induced by T. spiralis was of the rapid secondary type suggests that the parasites are resilient in the face of the inflammatory response capable of removing most of the worms. It is suggested that in addition to the immunomodulatory strategy employed by adult worms to prevent the intestinal response being elicited, the worms have a second line of defence which is reflected in their resilience to responses which they have been unable to prevent.
evasion of immunity
Remember meRedescription of Heligmosomoides neopolygyrus, Asakawa and Ohbayashi, 1986 (Nematoda: Heligmosomidae) from a Chinese rodent, Apodemus peninsulae (R...
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):367-74.Redescription of Heligmosomoides neopolygyrus, Asakawa and Ohbayashi, 1986 (Nematoda: Heligmosomidae) from a Chinese rodent, Apodemus peninsulae (Rodentia: Muridae); with comments on Heligmosomoides polygyrus polygyrus (Dujardin, 1845) and related species in China and Japan.1, , , .1Université Pierre et Marie Curie, Paris, UMR 7207 CNRS-MNHN-UPMC "Centre de recherche sur la Paléobiodiversité et les Paléoenvironnements - CR2P". MNHN, Paris Cedex, France.AbstractHeligmosomoides neopolygyrus, Asakawa and Ohbayashi, 1986 (Nematoda, Heligmosomoidea) is redescribed from Apodemus peninsulae from Rangtang, Sichuan, China. A morphological review of the Heligmosomoides spp. belonging to the "polygyrus line" proposed by Asakawa (1988) is made using new characters. This enabled us to distinguish two subspecies in Mus musculus (Heligmosomoides polygyrus bakeri from Japan and H. p. polygyrus from China) and two valid species in Apodemus spp. (H. neopolygyrus from Japan (in A. peninsulae) and from China (in A. agrarius) and H. asakawae from China (in A. uralensis)). Three parasite species of A. agrarius and A. peninsulae, previously identified by Asakawa et al. (1993) as H. neopolygyrus, are considered to be Heligmosomoides incertae sedis. This is the first report of H. neopolygyrus in A. peninsulae from China.PMID:
[PubMed - indexed for MEDLINE] Heligmosomoides neopolygyrus , in Apodemus peninsulae, from China: 1-6, male, anterior extremity, 1, right lateral view, 2-3, origin of cuticular ridges, 2, dorsal view, 3, right lateral view, 4, detail of excretory pore and deirids, ventral view, 5-6, origin of cuticular ridges, 5, left lateral view, 6, sub- 7-12, transverse sections of body, 7-9, male, 7, at level of esophago-intestinal junction, 8, at mid-body, 9, within distal fifth, 10-12, female, 10, at level of esophago-intestinal junction, 11, at midbody, 12, 13-15, male, 13, dorsal ray with rays 9 and 10, ventral view, 14, caudal bursa, ventral view, 15, spicules, in situ, 16, female, posterior extremity, right lateral view.Scale bar: : 100 μm. : 50 μm. : 20 μm. Abbreviations: de: deirids, r: right side, d: dorsal side, d.r.: dorsal ray, p.7: papillae 7. Transverse sections are oriented and numbered as in .Parasite. ):367-374.Caudal bursae of Heligmosomoides spp., from China, ventral views: 17, 18, H. p. polygyrus in Mus musculus, 17, from Shenyang, 18, from C 19, 20, H. neopolygyrus in Apodemus agrarius, 19, from Shenyang, 20, from C 21–23, Heligmosomoides incertae sedis, 21, in A. agrarius, from Antu, 22, in A. peninsulae, from Liang-Cheng, 23, in A. peninsulae, from Hulin. After
and modified.Scale bar: : 100 μm. Letters in brackets referred to
of . Grey bars show level of divergence of rays 4 and 5 and arising of rays 6 on the common trunk of rays 4 to 6: , in both lobes rays 6 arise proximally to the level of divergence of rays 4 and 5; , in left lobe ray 6 arising proximally to the level of divergence of rays 4 and 5, in right lobe at same level as the divergence of rays 4 and 5; , in both lobes rays 6 arising slightly distally to the level of divergence of rays 4 and 5; , in both lobes, rays 6 arise at same level as the divergence of rays 4 and 5.Parasite. ):367-374.Distribution of the species of the genus Heligmosomoides, belonging to the “polygyrus line” modified from
from China and Japan.Parasite. ):367-374.Publication TypesMeSH TermsGrant SupportFull Text Sources
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